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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3595 | Resmetirom | VIA-3196,MGL3196 | Thyroid hormone receptor(THR) |
Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist. | |||
T5313 | Sobetirome | IACS-010759,QRX-431 | Thyroid hormone receptor(THR) |
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM). | |||
T79089 | THR-β modulator-1 | ||
THR-β Modulator-1 (Compound 1a) is a potent modulator of the thyroid hormone receptor β, utilized in the study of thyroid hormone receptor-associated disorders [1]. | |||
T11954 | MB-07344 | Others | |
MB-07344 has additive cholesterol lowering activity in combination with Atorvastatin in rabbits, dogs and monkeys. MB-07344 is a potent thyroid hormone receptor (TR)-β agonist with a Ki of 2.17 nM. | |||
T63876 | TRβ agonist 1 | ||
TRβ Agonist 1, a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, demonstrates an EC50 value of 21 nM. It is useful in the research of dyslipidemia, nonalcoholic steatohepatitis (NASH), and resi... | |||
T11954L | MB-07344 sodium | Others | |
MB-07344 sodium has additive cholesterol lowering activity in combination with Atorvastatin in rabbits, dogs and monkeys. MB-07344 sodium is a potent thyroid hormone receptor (TR)-β agonist with a Ki of 2.17 nM. | |||
T74785 | THR-β agonist 6 | ||
THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μM for THR-β and 0.22 μM for THR-α. This compound boasts a remar... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06821 | THRB Protein, Human, Recombinant (His) | Human | E. coli |
Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin... |