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Search Results for " thyroid hormone receptor, β "

Targets

7

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T3595 Resmetirom VIA-3196,MGL3196 Thyroid hormone receptor(THR)
Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist.
T5313 Sobetirome IACS-010759,QRX-431 Thyroid hormone receptor(THR)
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
T79089 THR-β modulator-1
THR-β Modulator-1 (Compound 1a) is a potent modulator of the thyroid hormone receptor β, utilized in the study of thyroid hormone receptor-associated disorders [1].
T11954 MB-07344 Others
MB-07344 has additive cholesterol lowering activity in combination with Atorvastatin in rabbits, dogs and monkeys. MB-07344 is a potent thyroid hormone receptor (TR)-β agonist with a Ki of 2.17 nM.
T63876 TRβ agonist 1
TRβ Agonist 1, a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, demonstrates an EC50 value of 21 nM. It is useful in the research of dyslipidemia, nonalcoholic steatohepatitis (NASH), and resi...
T11954L MB-07344 sodium Others
MB-07344 sodium has additive cholesterol lowering activity in combination with Atorvastatin in rabbits, dogs and monkeys. MB-07344 sodium is a potent thyroid hormone receptor (TR)-β agonist with a Ki of 2.17 nM.
T74785 THR-β agonist 6
THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μM for THR-β and 0.22 μM for THR-α. This compound boasts a remar...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-06821 THRB Protein, Human, Recombinant (His) Human E. coli
Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin...
TargetMol